Penumbra Labs
Local-first inference runtime for regulated industries. Compresses frontier models onto on-prem hardware without retraining.
Frontier AI·Series A
Lattix
Vertical agents for property & casualty insurance. Replaces the email-PDF-spreadsheet underwriting loop.
Frontier AI·Lead
Marque
Evaluation infrastructure for production LLM systems. Regression testing for agents that change their minds.
Frontier AI·Seed
Threadwise
Legal workflow agents for mid-market firms. From discovery triage to first-pass drafting.
Frontier AI·Series B
Verident
Hallucination detection and provenance tracing for the enterprise. Used by three of the top ten US banks.
Frontier AI·Lead
Ossuary
Synthetic data generation for fraud and edge-case training. Closed-loop pipeline for hard-negative mining.
Frontier AI·Co-lead
Hygea Diagnostics
Multi-omic at-home risk screening for cardiovascular and metabolic disease. FDA-cleared, in-network with three national carriers.
Longevity·Series B
Senolytica
Senotherapeutic candidate in Phase 2 for age-related fibrosis. Co-developed with a top-five academic medical center.
Longevity·Lead
Prima Cycle
Reproductive longevity diagnostics and ovarian-aging assays. Direct-to-consumer with a clinician backbone.
Longevity·Series A
Continuum Vital
Always-on metabolic sensor with hormone-cycle aware analytics. Soft-launched in two US markets.
Longevity·Lead
Ironvane
Iron-air long-duration storage for utility-scale firming. Three GWh in committed offtake across MISO and ERCOT.
Climate·Series C
Bedrock Geo
Closed-loop geothermal with horizontal-drilling expertise from oil & gas operators. First pilot well producing as of Q4 2025.
Climate·Lead
Clearline Grid
Software layer for distribution-utility orchestration. Used in 14 IOUs and on Class 1 freight corridor electrification.
Climate·Series B
Tellur
Marine carbon removal with durable mineralization pathway. MRV-grade verification co-built with Lawrence Berkeley.
Climate·Co-lead
Mycelial Co.
Mycelium-grown structural composites for automotive interiors. Two OEM design wins announced for 2027 model year.
Synbio·Series A
Radium Bio
Microbial production of high-value pharma intermediates at petrochemical-comparable cost. Three contracts with top-twenty pharma.
Synbio·Lead
Pleiades Foundry
Bio-foundry-as-a-service with proprietary strain optimization. 11× faster design-build-test loops than incumbent CMOs.
Synbio·Lead
Heliforge Robotics
Autonomous fabrication arms for high-mix, low-volume metalwork. Deployed in 32 US fabrication shops.
Robotics·Series B
Tactile Compute
High-resolution skin-grade tactile sensors for dexterous manipulation. OEM-licensed to three humanoid programs.
Robotics·Lead
Coppervein
Remote-operations platform for industrial robotics. Hybrid autonomy with on-site supervisors and remote pilots.
Robotics·Co-lead
Brightwater
Functional hydration line built on electrolyte science from sports medicine. National retail across two major chains.
Consumer·Series A
Kestrel Sleep
Circadian-light therapy and at-home sleep diagnostics. CPT codes negotiated with two major payors.
Consumer·Series A
Meridian Mind
Eligibility and care-routing infrastructure for behavioral health. Used by 4,000 clinicians across 22 states.
Consumer·Lead
Axiomon
Document understanding for regulated industries. Acquired by a top-tier enterprise platform at 11.4× our entry valuation.
Frontier AI·Realized
Evergrid Storage
Utility-scale flow battery operator. Public on the NYSE since 2023. Astraeus held 4.2% pre-listing.
Climate·Public
Bionym Health
Continuous cardiac diagnostics platform. Acquired by a publicly traded diagnostics company at $1.2B.
Longevity·Realized